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EPA prioritizes risk assessment of five chemicals according to regulations



EPA prioritizes risk assessment of five chemicals according to regulations

Image source: EPA official website

The US Environmental Protection Agency (EPA) recently announced that it will prioritize risk assessments for five toxic chemicals under the US TSCA regulations. If the EPA designates these 5 chemicals as high priority substances during a 12 month legal process, risk assessments will begin for these chemicals.

These five chemicals are:

Acetaldehyde (CASRN 75-07-0)

Acetaldehyde is an organic compound mainly used in the production and processing of pharmaceuticals, petrochemical products, and dyes. It is an important intermediate in many synthetic materials. Exposure to acetaldehyde may cause harm to the human body, including the respiratory and digestive systems.

Acrylonitrile (CASRN 107-13-1)

Acrylonitrile is an important raw material for plastics, rubber, paint, coatings, adhesives, and fine chemical products. In general, the harm of acrylonitrile to the human body is mainly reflected in skin damage, respiratory irritation, and other aspects.

Aniline (CASRN 62-53-3)

Aniline is one of the most important amine substances. Mainly used for manufacturing dyes, drugs, resins, and can also be used as a rubber vulcanization promoter. Exposure to aniline may cause damage to multiple organs and tissues in humans, including the blood system, liver, nervous system, and skin.

4,4 '- Methylene bis (2-chloroaniline) (MBOCA) (CASRN 101-14-4)

MBOCA is mainly used as a vulcanizing agent for cast polyurethane rubber, a crosslinking agent for polyurethane coating adhesives, and can also be used as a curing agent for epoxy resins. A large amount of data suggests that exposure to MBOCA may damage genetic material in cells and cause other adverse effects.

Chloroethylene (CASRN 75-01-4)

Vinyl chloride is mainly used to manufacture polyvinyl chloride plastics (PVC), and can also be used to produce insulation materials, adhesives, coatings, refrigerants, etc. Exposure to vinyl chloride may have various hazards on human health, such as respiratory diseases, eye allergies, poisoning, etc.


In the future, the EPA expects to initiate a prioritization of 5 chemical substances annually, screening them as risk assessment substances, and creating a sustainable and effective environment for risk assessment. Prioritizing is the first step in EPA related regulatory authorization, assessing the need for health and environmental protection to regulate existing chemical substances currently on the market and in use.

This step also requires evaluating, sharing information, and providing processes to address the impact of toxic chemicals in use on workers, consumers, and communities as appropriate and necessary. If, at the end of the risk assessment process, the EPA determines that a chemical substance poses an unreasonable risk to health or the environment, it must immediately initiate a risk control program and take action to eliminate these unreasonable risks.


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